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Alzheimer’s and Diabetes: What’s the Connection?

Alzheimer’s and Diabetes: What’s the Connection?

When most people think about Alzheimer’s disease and diabetes, they picture two very different health problems, one affecting the brain, the other the body’s ability to control blood sugar. However, research shows the two are more connected than you might expect, with diabetes increasing the risk of Alzheimer’s disease by 59%.

At Kenneth K. Wogensen, MD, we believe understanding this link is essential for prevention, early diagnosis, and better long-term care.

A quick look at Alzheimer’s and diabetes

Alzheimer’s disease is the most common type of dementia. It causes progressive memory loss, confusion, and changes in thinking, behavior, and personality. Over time, it affects a person’s ability to manage daily activities independently.

Type 1 diabetes is an autoimmune disorder where the body attacks cells in your pancreas that produce insulin — the hormone that regulates blood sugar. Type 2 diabetes happens when the body doesn’t use insulin effectively (insulin resistance). In both cases, poor blood sugar control can severely damage organs, nerves, and blood vessels over time.

While these conditions may seem unrelated, scientists have discovered important overlaps.

How diabetes affects the brain

Your brain relies on a consistent supply of glucose (sugar) for energy. Insulin helps brain cells use glucose efficiently, but if there’s insulin resistance, the cells don’t respond properly to insulin. This can limit the brain’s access to the energy it needs to function well. Over time, poorly managed blood sugar can lead to:

Damaged blood vessels

Reduced blood flow results in less oxygen and nutrients reaching brain cells.

Inflammation

Chronic inflammation can harm brain tissue and speed up cognitive decline.

Increased plaque build-up

Similar to cholesterol plaques in arteries, the brain can develop harmful protein deposits linked to Alzheimer’s.

Some researchers use the term type 3 diabetes to describe Alzheimer’s disease in people with insulin resistance in the brain. While it’s not an official medical diagnosis, it highlights the idea that problems with insulin signaling may contribute to the brain changes seen in Alzheimer’s.

Shared diabetes and Alzheimer’s risk factors

Diabetes and Alzheimer’s share several risk factors, including:

Age

The risk of type 2 diabetes and dementia increases as you get older.

Family history

Genetics play a role in diabetes and dementia.

Unhealthy lifestyle habits

Poor diet, lack of exercise, and smoking are risk factors for both diseases.

High blood pressure and cholesterol

Hypertension (high blood pressure) and high cholesterol can impact blood flow to the brain and affect overall brain health.

Addressing these risk factors early helps protect both your brain and your body.

Alzheimer’s disease symptoms to watch for

If you have diabetes, it’s important to pay attention to signs of memory or thinking changes, such as:

Not every memory lapse means Alzheimer’s, but it’s worth discussing any instances with your doctor, especially if symptoms worsen over time.

Protecting your brain health when you have diabetes

Managing diabetes well can reduce your risk of Alzheimer’s and other forms of cognitive decline. Some key strategies include:

Keeping blood sugar in a healthy range

Work with your healthcare team to set goals and monitor your progress.

Adopting a brain-friendly diet

The dietary approaches to stop hypertension (DASH) and Mediterranean diets, rich in vegetables, fruits, whole grains, fish, and healthy fats, support better brain health.

Staying active

Physical exercise boosts blood flow to your brain and supports nerve cell growth.

Challenging your mind

Puzzles, reading, social interaction, and learning new skills keep the brain engaged.

Getting quality sleep

Sleep helps the brain clear waste products, including harmful proteins linked to Alzheimer’s.

Controlling blood pressure and cholesterol

Healthy circulation is essential for brain function.

Having diabetes doesn’t guarantee you’ll develop Alzheimer’s, but it does increase the risk. Understanding the connection means you can take steps now to protect your brain through healthy habits, medical care, and early screening.

We work closely with patients who have diabetes and are concerned about memory or cognitive changes. We provide:

Comprehensive evaluations

Assessments include memory testing, neurological exams, and imaging, if needed.

Personalized prevention plans

We offer tailored recommendations for diet, exercise, and lifestyle changes.

Medical management

We coordinate with your primary care provider or endocrinologist to optimize blood sugar control.

Ongoing support

We provide education for patients and families so they can better understand and manage Alzheimer’s symptoms if they arise.

At Kenneth K. Wogensen, MD, we’re committed to helping patients safeguard their cognitive health, whether that means preventing Alzheimer’s, slowing its progression, or supporting those already living with the condition. If you have diabetes and concerns about memory changes, call us, or use the online inquiry form to get in touch.

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